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Resolution enhancement of skeletal medical images and clinical application
- Clinical high-resolution (HR) skeletal images which can represent a bone microstructure are essential for accurate bone strength assessment. However, they are still unavailable because the current in vivo HR imaging modalities have a limited resolution due to high radiation doses, low signal-to-noise ratios, and/or long scan times.
- In this study, a HR skeletal image can be reconstructed from a clinical low-resolution (LR) image by applying topology optimization. The proposed method conducts localization/mesh refinement for resolution upscaling and then performs topology optimization with a constraint for the bone mineral density deviation to preserve the subject-specific bone distribution data.
- Although the topology optimization-based method shows the potential to reconstruct the bone microstructure from LR skeletal images, excessive computing time due to iterative large-scale FE analyses makes it impractical to be further implemented in the clinical field.
- To overcome the above obstacles, we propose a patchwise bone microstructure reconstruction scheme. HR skeletal images for training artificial neural network, which are difficult to obtain in clinical practice, can be replaced with the results from topology optimization-based bone remodeling.
Determination of the optimal operating condition for multi-receiver wireless power transfer systems
- In the single transmitter-single receiver systems, the resonant condition and electric performance can be calculated analytically. However, in the multiple-receiver systems, it is challenging to derive their explicit mathematical solutions because the receiver coils are coupled one another (i.e., higher system complexity). To enhance the performance of multi-receiver WPT systems, the break-through technologies are demanded.
- To solve the challenges of the multi-receiver WPT systems, we have two different approaches: optimal resonant condition and optimal load. In principle, the electric performance (e.g., transfer efficiency) can be adjusted by changing input voltage, capacitor, and loads in the WPT systems. Therefore, if the optimal resonant condition and/or optimal load can be determined, we can enhance the performance of the multi-receiver WPT systems and operate them in a more efficient and stable way
Determination of optimal resonant condition
Determination of optimal load condition
New Scheme for Representing a Vehicle Route: Loop-wise Route Representation
- Complex Vehicle Routing Problem (NP-Hard) is effectively addressed based on deep learning.
- The proposed novel loop-wise route presentation can be applied to route optimization for the Seoul metro.
